I began my career as a nurse with the expectation that much of my professional path would remain in hospitals. Now, after more than 15 years as an ICU RN, hospitalist APRN, and outpatient APRN, I know this is not necessarily the case. As APRNs continue to expand their roles in healthcare delivery, it is increasingly important for professionals to explore opportunities beyond traditional employment. APRN students can and should begin to explore the possibilities of independent practice after graduation. Independent practice and private practice ownership are no longer distant possibilities, but realistic options for APRNs who are willing and excited about the possibility to step into leadership.
APRN Entrepreneurship
Few graduate nursing programs teach APRNs how to build, operate, and sustain private practice. As a result, APRNs must depend on their professional network including mentors to learn how to operate their own private practice. Despite these challenges, graduate school provides a valuable opportunity to explore independent practice options and begin gathering the knowledge, resources, and connections needed for success. Below are some clear steps to help you get started as you consider independent practice.
The Value of Experience and State Practice Laws
Before formalizing a plan to open a private practice, it is important for APRNs to build the practical confidence and competency needed to succeed, whether through experience in a hospital, clinic, or healthcare organization. After building on their competencies, an APRN should familiarize themselves with their state’s practice requirements. Scope of practice laws can vary widely between states and determine whether physician collaboration is required.As of 2025, there are 30 U.S. states and territories, that allow APRNs to practice independently with Full Practice Authority (FPA) (Feeney, 2025). Upon licensure, the state of California offers FPA opportunity to nurse practitioners in a phased, step-wise manner, rather than full independence immediately (California Board of Registered Nursing, 2026). Therefore, it is important to check the specific legislation related to the state where you will practice.
Registering a Business
Once an APRN understands their state’s practice laws, they can establish their business structure. One option for operating a private practice is registering it as a Limited Liability Company (LLC). Registering as an LLC can often be completed through the Secretary of State’s website. Applicants are required to obtain an Employer Identification Number (EIN) and apply for a group National Provider Identifier (NPI) number. The process of securing a group NPI is similar to the process of securing an individual NPI.
Insurance, Collaboration, and Practice Tools
Securing malpractice insurance is another critical step for creating a private practice as an APRN. Practitioners who provide telehealth services should also consider coverage that includes cyber liability. Although occurrence-based malpractice coverage may be more expensive, it is often preferred for long-term protection. For practitioners working in states that require physician collaboration, a collaborating physician will need to be identified. It would be valuable to consider physicians who were previous colleagues. A collaborating physician can also be found through online platforms such as Single Aim, which connects APRNs with collaborating physicians. It is important to interview potential collaborators and ensure the partnership aligns with one’s goals and practice needs.
Finally, selecting an electronic medical record (EMR) system is essential. The best platforms are modern, user-friendly, and have reasonable billing and collection rates. Some EMR systems offer credentialing, billing, and revenue cycle management (RCM), which may reduce startup costs. When selecting an EMR, you may want to consider the following factors: HIPPA compliance, the use of AI for dictation, lab ordering and imaging order integration, built-in telehealth/video visit integration, patient portal functionality, E-signatures, and data encryption and backup systems.
Conclusion
Building an independent APRN practice requires preparation, persistence, and confidence. With proper planning and support, APRNs can successfully become independent providers and expand access to high-quality healthcare in their communities. To help students be better prepared in considering private practice opportunities, graduate nursing programs should consider offering courses or resources that can support students interested in establishing private practices.
References
Feeney, A. (2025). Nurse practitioner practice authority: A state-by-state guide. Nurse Journal.
California Board of Registered Nursing (BRN). (2026). Assembly Bill 890 (Wood, Chapter 265, Statues of 2020).